代表成果

1. Chang, X.; Cheng, X.; Liu, X. T.; Fu, C.; Wang, W. Y.; Wang, C. J., Stereodivergent Construction of 1,4-Nonadjacent Stereocenters via Hydroalkylation of Racemic Allylic Alcohols Enabled by Copper/Ruthenium Relay Catalysis. Angew. Chem. Int. Ed. 2022, 61, e202206517.

2.  Xiao, L.; Chang, X.; Xu, H.; Xiong, Q.; Dang, Y.; Wang, C. J., Cooperative Catalyst-Enabled Regio- and Stereodivergent Synthesis of alpha-Quaternary alpha-Amino Acids via Asymmetric Allylic Alkylation of Aldimine Esters with Racemic Allylic Alcohols. Angew. Chem. Int. Ed. 2022, 61, e202212948.

3. Yi, Z. Y.; Xiao, L.; Chang, X.; Dong, X. Q.; Wang, C. J., Iridium-Catalyzed Asymmetric Cascade Allylation/Retro-Claisen Reaction. J. Am. Chem. Soc. 2022, 144, 20025-20034.

4. Xiao, L.; Wei, L.; Wang, C. J., Stereodivergent Synthesis of Enantioenriched gamma-Butyrolactones Bearing Two Vicinal Stereocenters Enabled by Synergistic Copper and Iridium Catalysis. Angew. Chem. Int. Ed. 2021, 60, 24930-24940.

5. Che, C.; Li, Y.-N.; Cheng, X.; Lu, Y.-N.; Wang, C.-J., Visible-Light-Enabled Enantioconvergent Synthesis of α-Amino Acid Derivatives via Synergistic Brønsted Acid/Photoredox Catalysis. Angew. Chem. Int. Ed. 2021, 60, 4698-4704.

6. Chang, X.; Yang, Y.; Shen, C.; Xue, K.-S.; Wang, Z.-F.; Cong, H.; Tao, H.-Y.; Chung, L. W.; Wang, C.-J., β-Substituted Alkenyl Heteroarenes as Dipolarophiles in the Cu(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides Empowered by a Dual Activation Strategy: Stereoselectivity and Mechanistic Insight. J. Am. Chem. Soc. 2021, 143, 3519-3535.

7. Wei, L.; Chang, X.; Wang, C.-J., Catalytic Asymmetric Reactions with N-Metallated Azomethine Ylides. Acc. Chem. Res. 2020, 53, 1084-1100.

8.  Xu, S.-M.; Wei, L.; Shen, C.; Xiao, L.; Tao, H.-Y.; Wang, C.-J., Stereodivergent assembly of tetrahydro-γ-carbolines via synergistic catalytic asymmetric cascade reaction. Nat. Commun. 2019, 10, 5553.

9. Wei, L.; Zhu, Q.; Xiao, L.; Tao, H.-Y.; Wang, C.-J., Synergistic catalysis for cascade allylation and 2-aza-cope rearrangement of azomethine ylides. Nat. Commun. 2019, 10, 1594.

10. Wei, L.; Zhu, Q.; Xu, S.-M.; Chang, X.; Wang, C.-J., Stereodivergent synthesis of α,α-disubstituted α-amino acids via synergistic Cu/Ir catalysis. J. Am. Chem. Soc. 2018, 140, 1508-1513.

11. Wei, L.; Xu, S.-M.; Zhu, Q.; Che, C.; Wang, C.-J., Synergistic Cu/Pd catalysis for enantioselective allylic alkylation of aldimine esters: Access to α,α-disubstituted α-amino acids. Angew. Chem., Int. Ed. 2017, 56, 12312-12316.